drugset / Trial / NCT00877227

Does B Vitamin Supplementation Decrease Homocysteine Concentrations in Newborns

NCT00877227

Phase 1 Completed 37 enrolled Radboud University Medical Center
RandomizedSingle-groupOpen-labelBasic science

Summary

The purpose of this study is to determine whether supplementation with folinic acid, a B vitamin, lowers the concentrations of total homocysteine in newborns. Increased homocysteine concentrations are associated with an increased risk of cerebrovascular accidents in adult, children and newborns. These increased concentrations can easily and safely be lowered by folic acid in adults.

Timeline

Start
2003-01
Primary completion
2003-11
Completion
2003-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Leucovorin Small molecule 70 ug/kg Intravenous

Indications