drugset / Trial / NCT00879138
Efficacy and Safety of VA106483 in Elderly Males
RandomizedCrossoverDouble-blind
Summary
A double blind, placebo-controlled, dose ranging study in males over the age of 65, who have a history of nocturia. The study will investigate pharmacodynamic outcomes (urine volumes and osmolality, circulating coagulation factors and haemodynamics) and pharmacokinetics, of both single and multiple oral doses of VA106483 at three dose levels, under conditions of controlled hydration.
Timeline
- Start
- 2008-08
- Primary completion
- 2009-02
- Completion
- 2009-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | VA106483 | Small molecule | 2 mg | Oral |
| Subject | VA106483 | Small molecule | 4 mg | Oral |
| Subject | VA106483 | Small molecule | 8 mg | Oral |
Indications
No indication recorded.