drugset / Trial / NCT00885196

A Dose Finding Study of AEB071 Assessing Psoriasis Area and Severity Index in Patients With Plaque Psoriasis

NCT00885196

Phase 2 Completed 336 enrolled Novartis Pharmaceuticals
RandomizedParallel-groupDouble-blindTreatment

Summary

This study is designed to provide efficacy and safety data of several doses of AEB071 so that the optimal dose and treatment duration can be chosen for testing in later studies in patients with plaque psoriasis (with a disease severity such that systemic treatment is justified). The treatment free Follow-up Period is designed to provide additional safety data and information on disease recurrence after the last dose of the study drug.

Timeline

Start
2009-04
Primary completion
2011-08
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject sotrastaurin Small molecule 200 mg Oral
Subject sotrastaurin Small molecule 300 mg Oral
Subject sotrastaurin Small molecule 400 mg Oral

Indications