A Randomized Controlled Trial Comparing Two Timing Regimens of Pico-salax for Colon Cleansing Prior to Colonoscopy

Phase 4 Completed 250 enrolled Queen's University

RandomizedParallel-groupDouble-blindDiagnostic

Summary

Pico-Salax is an osmotic and stimulant bowel cleansing agent used prior to colonoscopy. It is unknown whether splitting the doses (i.e. taking the second dose the morning of the colonoscopy) results in a better bowel cleansing, as research with other agents suggests this may be the case. This study aims to assess whether splitting the dose of Pico-Salax results in a better bowel cleansing than traditional dosing.

Timeline

Start: 2008-11
Primary completion: 2011-03
Completion: 2011-08

Publications

Flemming JA, Vanner SJ, Hookey LC. Split-dose picosulfate, magnesium oxide, and citric acid solution markedly enhances colon cleansing before colonoscopy: a randomized, controlled trial. Gastrointest Endosc. 2012 Mar;75(3):537-44. doi: 10.1016/j.gie.2011.09.018. Epub 2011 Dec 21.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Sodium Picosulfate	Unknown	—	—

Indications

No indication recorded.