drugset / Trial / NCT00885690
Comparing the Effects of Sertindole and Olanzapine on Cognition (SEROLA)
Terminated
11 enrolled
University of Aarhus
Aalborg Psychiatric Hospital · collabMalmö University · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Cognition is one of the core symptoms of schizophrenia. This study is a head-to-head trial between olanzapine and sertindole with cognition as primary outcome. The design is a 12-week double-blinded randomized controlled flexible dose study.
Timeline
- Start
- 2009-04
- Primary completion
- 2012-11
- Completion
- 2012-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Olanzapine | Small molecule | 10 mg | — |
| Comparator | Olanzapine | Small molecule | 20 mg | — |
| Comparator | Sertindole | Small molecule | 16 mg | — |
| Comparator | Sertindole | Small molecule | 24 mg | — |