drugset / Trial / NCT00886405

Concurrent Chemotherapy and Radiotherapy With Nitroglycerin in Patients With Locally Advanced Non-Small Cell Lung Cancer

NCT00886405

Phase 2 Unknown 40 enrolled National Institute of Cancerology
Non-randomizedSingle-groupOpen-labelTreatment

Summary

Nitroglycerin will increase the effectiveness of treatment with induction chemotherapy and concurrent chemo-radiotherapy by reducing chemo-radio resistance through an increased oxygen pressure in tumoral tissue. The combination treatment of nitroglycerin and chemotherapy will result in longer disease-free and over-all survival in patients with locally advanced NSCLC

Timeline

Start
2006-07
Primary completion
2009-04
Completion
2010-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Nitroglycerin Unknown 25 mg Other