drugset / Trial / NCT00887120
Dose Reduction of Lopinavir in Children
Phase 2
Completed
24 enrolled
The HIV Netherlands Australia Thailand Research Collaboration
Ministry of Education, Thailand · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
To study the pharmacokinetics of low-dose and standard dose, lopinavir/ritonavir in ARV PI naive HIV-1 infected Thai children. To study clinical and immunological efficacy after 48 weeks of lopinavir/ritonavir in PI naïve HIV-1 infected Thai children
Timeline
- Start
- 2007-04
- Primary completion
- 2009-01
- Completion
- 2009-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Lopinavir/ritonavir | Unknown | 1 ml | Oral |
| Comparator | Lopinavir/ritonavir | Unknown | 1.5 ml | Oral |
| Comparator | Lopinavir/ritonavir | Unknown | 1.8 ml | Oral |
| Comparator | Lopinavir/ritonavir | Unknown | 2 ml | Oral |
| Comparator | Lopinavir/ritonavir | Unknown | 2.5 ml | Oral |
| Comparator | Lopinavir/ritonavir | Unknown | 3 ml | Oral |
| Comparator | Lopinavir/ritonavir | Unknown | 3.5 ml | Oral |
| Comparator | Lopinavir/ritonavir | Unknown | 4 ml | Oral |
| Comparator | Lopinavir/ritonavir | Unknown | 5 ml | Oral |