drugset / Trial / NCT00889629
Pilot Study Evaluating Doxercalciferol Replacement Therapy in Kidney Transplant Recipients
RandomizedParallel-groupTriple-blindTreatment
Summary
People with kidney transplants often develop bone disease. One reason for bone disease may be overactivity of a gland in the neck called the parathyroid gland. Overactivity of the parathyroid gland may be caused by lack of Vitamin D in the body. It has recently been discovered that many patients with kidney transplants have low Vitamin D levels. The investigators are examining the effects of doxercalciferol on parathyroid hormone levels, proteinuria and bone turnover markers in people who have had a kidney transplant.
Timeline
- Start
- 2008-11
- Primary completion
- 2010-01
- Completion
- 2010-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Doxercalciferol | Small molecule | 1 ug | — |
| Background | Cholecalciferol | Other / unclassified | 400 iu | — |