drugset / Trial / NCT00890279

Efficacy and Safety Study of Second-Line Treatment for Hypertension With Autosomal Dominant Polycystic Kidney Disease(ADPKD)

NCT00890279

Phase 2 Unknown 160 enrolled Ministry of Health, Labour and Welfare, Japan
RandomizedParallel-groupOpen-labelTreatment

Summary

This phase II study examines the safety and efficacy of combination therapy for hypertension in patients with autosomal dominant polycystic kidney disease (ADPKD). This study examines the safety and efficacy of combination therapy by imidapril (ACEI) or cilnidipine (CCB) in ADPKD patients whose blood pressure is not controlled under 120/80 mmHg by candesartan (ARB) alone.

Timeline

Start
2009-07
Primary completion
2010-06
Completion
2012-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Cilnidipine Small molecule 20 mg
Comparator Imidapril Small molecule 10 mg