drugset / Trial / NCT00890279
Efficacy and Safety Study of Second-Line Treatment for Hypertension With Autosomal Dominant Polycystic Kidney Disease(ADPKD)
RandomizedParallel-groupOpen-labelTreatment
Summary
This phase II study examines the safety and efficacy of combination therapy for hypertension in patients with autosomal dominant polycystic kidney disease (ADPKD). This study examines the safety and efficacy of combination therapy by imidapril (ACEI) or cilnidipine (CCB) in ADPKD patients whose blood pressure is not controlled under 120/80 mmHg by candesartan (ARB) alone.
Timeline
- Start
- 2009-07
- Primary completion
- 2010-06
- Completion
- 2012-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cilnidipine | Small molecule | 20 mg | — |
| Comparator | Imidapril | Small molecule | 10 mg | — |