drugset / Trial / NCT00890318
A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetic Profiles of Multiple Doses of ABT-072 Used to Treat Hepatitis C
RandomizedSingle-groupQuadruple-blind
Summary
The purpose of this study is to determine multiple dose safety, tolerability and pharmacokinetics of ABT-072 under nonfasting conditions in healthy adult subjects, and to determine the effect of single dose administration of ketoconazole on steady state ABT-072 pharmacokinetics.
Timeline
- Start
- 2009-04
- Primary completion
- 2009-07
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ABT-072 | Small molecule | 80 mg | — |
| Subject | ABT-072 | Small molecule | 160 mg | — |
| Subject | ABT-072 | Small molecule | 320 mg | — |
| Subject | Ketoconazole | Small molecule | 400 mg | — |