drugset / Trial / NCT00896298
Trial of Leptin Replacement Therapy in Patients With Lipodystrophy
RandomizedParallel-groupTriple-blindTreatment
Summary
Lipodystrophies represent a therapeutic challenge with regards to insulin resistance, hypertriglyceridemia and fatty liver which often is coupled with significant adipose tissue loss. The purpose of the study is to examine the safety and efficacy of Leptin on subjects with lipodystrophy.
Timeline
- Start
- 2006-04
- Primary completion
- 2014-11
- Completion
- 2014-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Leptin | Protein / enzyme biologic | 0.02 mg/kg | Subcutaneous |
| Comparator | Leptin | Protein / enzyme biologic | 0.03 mg/kg | Subcutaneous |
| Comparator | Leptin | Protein / enzyme biologic | 0.04 mg/kg | Subcutaneous |