A Study of FV-100 Versus Valacyclovir in Patients With Herpes Zoster

Summary

The purpose of this study is to compare the safety and efficacy of two doses of FV-100 to valacyclovir in patients with herpes zoster, or shingles. FV-100 has shown to be very potent in cells infected with varicella zoster virus, the virus that causes shingles. The study objectives include: * Compare the safety of FV-100 to valacyclovir * Compare the effect of FV-100, as compared to valacyclovir, on shingles pain * Compare the effect of FV-100, as compared to valacyclovir, on shingles lesions

Timeline

Start

2009-05

Primary completion

2010-11

Completion

2010-12

Publications

• Tyring SK, Lee P, Hill GT Jr, Silverfield JC, Moore AY, Matkovits T, Sullivan-Bolyai J. FV-100 versus valacyclovir for the prevention of post-herpetic neuralgia and the treatment of acute herpes zoster-associated pain: A randomized-controlled trial. J Med Virol. 2017 Jul;89(7):1255-1264. doi: 10.1002/jmv.24750. Epub 2016 Dec 26.

Drugs

Indications