drugset / Trial / NCT00902031
Effectiveness of Docusate in Preventing/Treating Constipation in Palliative Care Patients
Completed
70 enrolled
University of Alberta
Capital Care · collabCollege of Family Physicians of Canada · collabCovenant Health, Canada · collab
RandomizedParallel-groupQuadruple-blindPrevention
Summary
The purpose of this study is to determine if docusate is effective in the treatment of constipation in palliative care patients.
Timeline
- Start
- 2006-04
- Primary completion
- 2010-10
- Completion
- 2010-10
Publications
- Background CASS LJ, FREDERIK WS. Doxinate in the treatment of constipation. Am J Gastroenterol. 1956 Dec;26(6):691-8. No abstract available.
- Background Castle SC, Cantrell M, Israel DS, Samuelson MJ. Constipation prevention: empiric use of stool softeners questioned. Geriatrics. 1991 Nov;46(11):84-6. No abstract available.
- Background Fain AM, Susat R, Herring M, Dorton K. Treatment of constipation in geriatric and chronically ill patients: a comparison. South Med J. 1978 Jun;71(6):677-80. doi: 10.1097/00007611-197806000-00022.
- Background Goodman J, Pang J, Bessman AN. Dioctyl sodium sulfosuccinate- an ineffective prophylactic laxative. J Chronic Dis. 1976 Jan;29(1):59-63. doi: 10.1016/0021-9681(76)90068-0. No abstract available.
- Background Hurdon V, Viola R, Schroder C. How useful is docusate in patients at risk for constipation? A systematic review of the evidence in the chronically ill. J Pain Symptom Manage. 2000 Feb;19(2):130-6. doi: 10.1016/s0885-3924(99)00157-8.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Docusate Sodium | Unknown | 200 mg | Oral |
| Background | Senna | Traditional medicine (herbal / TCM) | 8.6 mg | Oral |