Methadone Maintenance Treatment and Smoking Cessation

Summary

The main hypotheses guiding the study are: 1. Stable methadone maintenance patients receiving varenicline will be more likely to maintain abstinence than patients receiving placebo 2. There will be no differences in the type and number of symptoms reported between stable methadone maintenance patients receiving varenicline and placebo 3. There will be no changes in methadone dosage between abstinent and non-abstinent smokers 4. There will be no differences in efficacy, withdrawal symptoms, and safety of varenicline between male and female participants

Timeline

Start

2009-05

Primary completion

2009-10

Completion

2011-02

Publications

• Livingstone-Banks J, Fanshawe TR, Thomas KH, Theodoulou A, Hajizadeh A, Hartman L, Lindson N. Nicotine receptor partial agonists for smoking cessation. Cochrane Database Syst Rev. 2023 May 5;5(5):CD006103. doi: 10.1002/14651858.CD006103.pub8.

Drugs

Indications

No indication recorded.