drugset / Trial / NCT00908453
The Study of NPC-06 - Investigation of Safety, Efficacy and Pharmacokinetics of Fosphenytoin
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The study is to evaluate safety, efficacy and pharmacokinetics of intravenously administered fosphenytoin in patients with neurosurgery, head trauma, epilepsy or status epilepticus who are requiring a loading dose of phenytoin.
Timeline
- Start
- 2009-05
- Primary completion
- 2010-02
- Completion
- 2010-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fosphenytoin | Small molecule | 15 mg/kg | Intravenous |
| Subject | Fosphenytoin | Small molecule | 18 mg/kg | Intravenous |
| Subject | Fosphenytoin | Small molecule | 22.5 mg/kg | Intravenous |