drugset / Trial / NCT00909857
Effect on Primary Dysmenorrhea
RandomizedParallel-groupTriple-blindTreatment
Summary
To investigate the potential benefits of a new oral contraceptive (SH T00658ID) on alleviating complaints of dysmenorrhea associated with oral contraceptive use.
Timeline
- Start
- 2009-04
- Primary completion
- 2010-11
- Completion
- 2010-11
Outcome
Missed primary endpoint
paper for the E(2)V/DNG and EE/LNG groups, respectively (P = 0.34). PMID 24713413 ↗
Publications
- Schroll JB, Black AY, Farquhar C, Chen I. Combined oral contraceptive pill for primary dysmenorrhoea. Cochrane Database Syst Rev. 2023 Jul 31;7(7):CD002120. doi: 10.1002/14651858.CD002120.pub4.
- Petraglia F, Parke S, Serrani M, Mellinger U, Romer T. Estradiol valerate plus dienogest versus ethinylestradiol plus levonorgestrel for the treatment of primary dysmenorrhea. Int J Gynaecol Obstet. 2014 Jun;125(3):270-4. doi: 10.1016/j.ijgo.2013.11.017. Epub 2014 Mar 11.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dienogest | Small molecule | — | Oral |
| Comparator | Levonorgestrel | Small molecule | — | Oral |
| Subject | estradiol valerate | Unknown | — | Oral |
| Comparator | ethinyl estradiol | Small molecule | — | Oral |