Effects of Etanercept on the Heart, Veins and Thickness of Certain Major Arteries In Ankylosing Spondylitis Patients

Summary

Study to assess whether etanercept therapy is able to increase flow-mediated vasodilatation in AS, and whether etanercept can modify the intima-media thickness (IMT) in these patients

Timeline

Start

2009-07

Primary completion

2011-10

Completion

2011-10

Outcome

Missed primary endpoint

registry analysis (superiority or other test); Etanercept vs Placebo; p = 0.608; Mean Difference (Final Values) 1.72 (95% CI -5.14 to 8.58); Mixed Models Analysis NCT00910273 ↗

Drugs

Indications