Vitamin D Supplementation and CD4 Count in HIV-Infected Children

Summary

To find out if vitamin D supplementing can lead to an improvement in immunological status in HIV-infected children as part of routine clinical care

Timeline

Start

2009-02

Primary completion

2009-10

Completion

2010-07

Outcome

Missed primary endpoint

paper Vitamin D supplementation did not lead to an increase in CD4 percent or CD4 count. PMID 21820130 ↗

paper Vitamin D supplementation in doses as high as 1600 IU/day does not impact CD4 count. PMID 21820130 ↗

Publications

• Kakalia S, Sochett EB, Stephens D, Assor E, Read SE, Bitnun A. Vitamin D supplementation and CD4 count in children infected with human immunodeficiency virus. J Pediatr. 2011 Dec;159(6):951-7. doi: 10.1016/j.jpeds.2011.06.010. Epub 2011 Aug 4.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Vitamin D	Other / unclassified	5600 iu	—
Subject	Vitamin D	Other / unclassified	11200 iu	—

Indications