drugset / Trial / NCT00914017
Statins and Breast Cancer Biomarkers
Phase 2
Unknown
100 enrolled
University of Vermont
Breast Cancer Research Foundation · collabCancer and Leukemia Group B · collab
RandomizedParallel-groupTriple-blindPrevention
Summary
There is laboratory evidence that cholesterol lowering medications (statins) inhibit the growth of breast cancer cells. Clinical studies are controversial but some show that women taking statins are less likely to get breast cancer. This ongoing randomized trial compares one-year of atorvastatin (Lipitor™) or placebo for lowering mammography-defined breast density and other surrogate markers associated with breast cancer risk.
Timeline
- Start
- 2005-01
- Primary completion
- 2010-12
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Atorvastatin | Small molecule | 40 mg | — |