drugset / Trial / NCT00914628

Efficacy Study on the Strategy of HSV-Tk Engineering Donor Lymphocytes to Treat Patients With High Risk Acute Leukemia

NCT00914628

Phase 3 Terminated 92 enrolled AGC Biologics S.p.A.
RandomizedParallel-groupOpen-labelTreatment

Summary

The main objective of this randomized trial is to compare disease-free survival (DFS) in high risk leukemia patients who underwent haploidentical HCT followed by an add back strategy of HSV-Tk donor lymphocytes or standard haploidentical HCT

Timeline

Start
2010-04-12
Primary completion
2019-11-30
Completion
2019-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject HSV-Tk Cell therapy 1e+07 cells/kg

Indications