drugset / Trial / NCT00916097
NPC Study : TAX + CIS Neoadjuvant in Patients With Loco Regionally Advanced Undifferentiated Carcinoma of Nasopharyngeal Type (UCNT)
Non-randomizedSingle-groupOpen-labelTreatment
Summary
Primary Objective: To estimate the overall response rate after neo-adjuvant chemotherapy of Docetaxel 75 mg/m2 in combination with Cisplatin 75 mg/m2 given for 3 cycles, and followed by conventional radiotherapy in UCNT. Secondary Objectives: To evaluate: * The radiological response after chemotherapy and radiotherapy * The pathological response after chemotherapy by cavum biopsy To estimate: * The duration of overall response * The time to progression (T.T.P) To analyze: * The overall survival * The safety profile
Timeline
- Start
- 2002-07
- Primary completion
- 2005-11
- Completion
- 2005-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Docetaxel | Small molecule | 75 mg/m2 | Intravenous |