Pharmacokinetics of 3 Formulations of Ibuprofen Suppositories

Phase 1 Completed 25 enrolled Johnson & Johnson Consumer and Personal Products Worldwide

RandomizedCrossoverOpen-labelBasic science

Summary

The purpose of this study is to compare the pharmacokinetic and bioavailability characteristics of two test formulations of ibuprofen for rectal administration with the profile of a marketed reference formulation of ibuprofen 200 mg (for oral administration).

Timeline

Start: 2004-04
Primary completion: 2004-07
Completion: 2004-11

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ibuprofen	Small molecule	50 mg	Rectal
Subject	Ibuprofen	Small molecule	200 mg	Rectal

Indications

No indication recorded.