drugset / Trial / NCT00925587
Evaluation of Monthly Darbepoetin Alfa Dosing for Correction of Anemia in Non-dialysis Chronic Kidney Disease
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to determine whether once monthly (QM) dosing of darbepoetin alfa is non-inferior to that of once every 2 week (Q2W) dosing of darbepoetin alfa for the correction of anemia in patients with Chronic Kidney Disease who are not receiving dialysis.
Timeline
- Start
- 2009-06
- Primary completion
- 2012-04
- Completion
- 2012-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Darbepoetin alfa | Protein / enzyme biologic | 10 ug | — |
| Comparator | Darbepoetin alfa | Protein / enzyme biologic | 20 ug | — |
| Comparator | Darbepoetin alfa | Protein / enzyme biologic | 30 ug | — |
| Comparator | Darbepoetin alfa | Protein / enzyme biologic | 40 ug | — |
| Comparator | Darbepoetin alfa | Protein / enzyme biologic | 50 ug | — |
| Comparator | Darbepoetin alfa | Protein / enzyme biologic | 60 ug | — |
| Comparator | Darbepoetin alfa | Protein / enzyme biologic | 80 ug | — |
| Comparator | Darbepoetin alfa | Protein / enzyme biologic | 100 ug | — |
| Comparator | Darbepoetin alfa | Protein / enzyme biologic | 130 ug | — |
| Comparator | Darbepoetin alfa | Protein / enzyme biologic | 150 ug | — |
| Comparator | Darbepoetin alfa | Protein / enzyme biologic | 200 ug | — |
| Comparator | Darbepoetin alfa | Protein / enzyme biologic | 300 ug | — |
| Comparator | Darbepoetin alfa | Protein / enzyme biologic | 400 ug | — |
| Comparator | Darbepoetin alfa | Protein / enzyme biologic | 600 ug | — |