Tolcapone Treatment of Pathological Gambling

Summary

The goal of the proposed study is to evaluate the efficacy and safety of tolcapone in pathological gambling.

Timeline

Start

2009-06

Primary completion

2012-05

Completion

2012-07

Publications

• Grant JE, Odlaug BL, Chamberlain SR, Hampshire A, Schreiber LR, Kim SW. A proof of concept study of tolcapone for pathological gambling: relationships with COMT genotype and brain activation. Eur Neuropsychopharmacol. 2013 Nov;23(11):1587-96. doi: 10.1016/j.euroneuro.2013.07.008. Epub 2013 Aug 6.

Drugs

Indications