Cross-over Comparison of Gabapentin and Memantine as Treatment for Acquired Nystagmus

Summary

Involuntary oscillations of the eyes (nystagmus) impairs vision so that affected patients, who have neurological disorders such as Multiple Sclerosis (MS) , cannot read or watch TV. Two medicines have been reported to suppress nystagmus and improve vision in such patients: gabapentin and memantine. The investigators set out to test which of these two drug was more effective by carrying out a double-blind cross-over study. In this way, we could determine which drug worked best in each patient.

Timeline

Start

2005-02

Primary completion

2009-05

Completion

2009-05

Drugs

Indications