A Study of RO4998452 in Type 2 Diabetes Patients With Varying Degrees of Renal Impairment

Summary

This 4 arm study will investigate the pharmacodynamics and pharmacokinetics of RO4998452 in type 2 diabetes patients with varying degrees of renal impairment. Eligible patients will be divided into 4 groups, with normal renal function, or mild, moderate or severe renal impairment. All patients will receive a single oral dose of RO4998452 in the fasted state.The anticipated time on study treatment is \<3 months (single dose study)and the target sample size is \<100 individuals.

Timeline

Start

2009-06

Primary completion

2010-09

Completion

2010-09

Drugs

Indications