drugset / Trial / NCT00934466
Study of the Effect of Single Doses of MK2637 and Dextromethorphan on Cerebral Cortex Excitability (2637-008)
RandomizedCrossoverDouble-blindDiagnostic
Summary
This study will assess transcranial magnetic stimulation (TMS) as a biomarker and characterize TMS readouts of the activity of MK2637 and dextromethorphan. Resting quantitative electroencephalography(qEEG) readouts are also characterized with MK2637 and dextromethorphan.
Timeline
- Start
- 2009-07
- Primary completion
- 2009-12
- Completion
- 2009-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dextromethorphan | Unknown | 110 mg | — |
| Comparator | Dextromethorphan | Unknown | 220 mg | — |
| Subject | MK2637 | Unknown | 50 mg | — |
| Subject | MK2637 | Unknown | 120 mg | — |