drugset / Trial / NCT00935363
Interplay Between Organic Anion Transporting Polypeptide (OATP) Transporters Transporters and CYP2C9 in Glyburide Pharmacokinetics (PK)
RandomizedCrossoverOpen-labelBasic science
Summary
The purpose of this study is to investigate if the drugs rifampin and fluconazole when given together increase the concentrations in the body of the oral diabetes medication glyburide.
Timeline
- Start
- 2010-02
- Primary completion
- 2010-03
- Completion
- 2010-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fluconazole | Small molecule | — | Intravenous |
| Comparator | Glyburide | Small molecule | — | Oral |
| Subject | Rifampin | Small molecule | — | Intravenous |
Indications
No indication recorded.