drugset / Trial / NCT00936546

A Protocol Based Treatment for Debilitating Fibrosing Skin Disorders With (Anti-CD 20), Rituximab, Evaluating Safety and Efficacy

NCT00936546 ↗

Phase 2 Completed 3 enrolled University Hospital, Ghent
NaSingle-groupOpen-labelTreatment

Summary

This study will evaluate the safety and efficacy of the combination of rituximab and methotrexate to treat disabling fibrosing skin disorders.Rituximab will be administered at baseline and month 6. The drug will be considered efficacious if the skin thickness diminishes substantially.

Timeline

Start
2009-06
Primary completion
2015-06-03
Completion
2015-06-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Rituximab Monoclonal antibody 1000 mg Intravenous