drugset / Trial / NCT00941681
Pharmacokinetics of Oral CK-1827452 in Patients With Stable Heart Failure
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is designed to understand the pharmacokinetics of different oral formulations of CK-1827452 being considered for future studies in patients with heart failure. This study will compare the pharmacokinetics and safety and tolerability of both modified-release (MR) and immediate-release (IR) oral formulations of CK-1827452.
Timeline
- Start
- 2009-04
- Primary completion
- 2009-10
- Completion
- 2009-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Omecamtiv Mecarbil | Small molecule | 37.5 mg | Oral |
| Subject | Omecamtiv Mecarbil | Small molecule | 50 mg | Oral |
| Subject | Omecamtiv Mecarbil | Small molecule | 100 mg | Oral |