drugset / Trial / NCT00942214

Biomarkers and Response to Natalizumab for Multiple Sclerosis Treatment

NCT00942214

Phase 4 Completed 300 enrolled University Hospital, Toulouse
NaSingle-groupOpen-labelDiagnostic

Summary

Information from blood samples may help us for choosing the best treatment in future personalized medicine. Natalizumab (NTZ) a current treatment for MS can be used as a second line therapy if a suboptimal response to disease modifying drugs. When to introduce NTZ is not consensual. The investigators hypothesized that biological information could rationalize choice and thus designed a prospective open label trial to test biological markers before treatment.

Timeline

Start
2009-06
Primary completion
2011-02
Completion
2011-03

Drugs

EvaluationDrugModalityDoseRoute
Subject natalizumab Monoclonal antibody 300 mg Intravenous

Indications