drugset / Trial / NCT00942838

Whole Abdomen Radiation in Conjunction With Intraperitoneal Chemotherapy for the Treatment of Small Volume Recurrent Ovarian Carcinoma Limited to the Peritoneal Cavity

NCT00942838 ↗

Phase 1 Withdrawn University of Utah
NaSingle-groupOpen-labelTreatment

Summary

The proposed study is a prospective cohort study incorporating patients with first recurrence ovarian or primary peritoneal cancer who will receive intraperitoneal chemotherapy in conjunction with whole abdomen radiation. The primary end point of this investigator initiated research study is to determine the toxicity associated with whole abdomen radiation in combination with intraperitoneal chemotherapy. Primary Objective: * Determine the maximum tolerated dose (MTD) of whole abdomen radiation in conjunction with intraperitoneal cisplatin chemotherapy in the treatment of women with small volume (\< 1 cm) recurrent ovarian cancer confined to the abdominal peritoneal cavity. Secondary Objective: * Quality of Life assessment.

Timeline

Start
2009-07
Primary completion
2010-04
Completion
2010-04

Outcome

Outcome not reported

Stopped (Enrollment): “PI decision due to under accrual.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Cisplatin Other / unclassified — Intrathecal

Indications