drugset / Trial / NCT00945256
Muscle Perfusion and Protein Metabolism in Elderly
Phase 1
Completed
62 enrolled
The University of Texas Medical Branch, Galveston
National Institute on Aging (NIA) · collab
RandomizedFactorialOpen-label
Summary
The purpose of this study was to examine the role skeletal muscle perfusion plays in mediating muscle protein synthesis in healthy older and younger individuals. The investigators hypothesized that normalization of muscle perfusion in older men and women via exercise or infusion of a vasodilator would enhance nutritive flow and skeletal muscle protein synthesis in the elderly similar to that of their younger counterparts.
Timeline
- Start
- 2003-05
- Primary completion
- 2008-05
- Completion
- 2009-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Sodium Nitroprusside | Unknown | 0.114 ug/kg | — |
Indications
No indication recorded.