Effect of Exenatide on Glucose Homeostasis Determinants in Type 2 Diabetes

Summary

The purpose of this study is to determine in type 2 diabetic patients in secondary failure to combined oral therapy whether, besides improvement in glycemic control, addition of exenatide, a new drug introduced to treat diabetes before addition of insulin to current therapy, over 6 months is associated with improvement in beta-cell function, insulin sensitivity following 24-hours discontinuation of the drug.

Timeline

Start

2008-07

Primary completion

2009-07

Completion

2009-07

Drugs

Indications