drugset / Trial / NCT00949065
Intravenous Immunoglobulins in Complex-regional Pain Syndrome
RandomizedCrossoverQuadruple-blindTreatment
Summary
The purpose of this study is to determine whether intravenous immunoglobulins are effective in the treatment of complex-regional pain syndrome.
Timeline
- Start
- 2009-08
- Primary completion
- 2011-01
- Completion
- 2011-02-15
Publications
- Background Kohr D, Tschernatsch M, Schmitz K, Singh P, Kaps M, Schafer KH, Diener M, Mathies J, Matz O, Kummer W, Maihofner C, Fritz T, Birklein F, Blaes F. Autoantibodies in complex regional pain syndrome bind to a differentiation-dependent neuronal surface autoantigen. Pain. 2009 Jun;143(3):246-251. doi: 10.1016/j.pain.2009.03.009. Epub 2009 Apr 16.
- Background Goebel A, Stock M, Deacon R, Sprotte G, Vincent A. Intravenous immunoglobulin response and evidence for pathogenic antibodies in a case of complex regional pain syndrome 1. Ann Neurol. 2005 Mar;57(3):463-4. doi: 10.1002/ana.20400. No abstract available.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Immune Globulin Intravenous (Human) | Protein / enzyme biologic | 0.36 g/kg | Intravenous |
| Comparator | Immune Globulin Intravenous (Human) | Protein / enzyme biologic | 0.44 g/kg | Intravenous |