Measuring Responses to Sublingual Antigens

Completed 18 enrolled St George's, University of London European Union · collab

Non-randomizedParallel-groupOpen-labelBasic science

Summary

This study is a preliminary investigation of immune responses, in the blood and in cervical \& vaginal secretions, to proteins ("antigens") taken up across the undersurface of the tongue.

Timeline

Start: 2009-09
Primary completion: 2010-06
Completion: 2011-01

Publications

Huo Z, Bissett SL, Giemza R, Beddows S, Oeser C, Lewis DJ. Systemic and mucosal immune responses to sublingual or intramuscular human papilloma virus antigens in healthy female volunteers. PLoS One. 2012;7(3):e33736. doi: 10.1371/journal.pone.0033736. Epub 2012 Mar 16.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Gardasil	Vaccine	0.5 ml	Intramuscular

Measuring Responses to Sublingual Antigens

Summary

Timeline

Publications

Drugs

Indications