drugset / Trial / NCT00951457
Bendamustine Combined With Alemtuzumab in Pretreated Chronic Lymphocytic Leukemia (CLL)
Phase 1/2
Completed
20 enrolled
Study Group of Medical Tumour Therapy (AGMT)
Mundipharma Pte Ltd. · collab
NaSingle-groupOpen-labelTreatment
Summary
The primary objective of this study is to determine the percentage of patients achieving a response, defined as the percentage of patients achieving complete response, partial response and stable disease/ no change upon treatment with the combination therapy according to NCI response criteria (also established according to IWCLL guidelines) upon treatment with a combination of bendamustine and alemtuzumab.
Timeline
- Start
- 2009-03
- Primary completion
- 2012-08-06
- Completion
- 2012-08-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Alemtuzumab | Monoclonal antibody | 30 mg | Subcutaneous |
| Subject | Bendamustine | Small molecule | 70 mg/m2 | Intravenous |