drugset / Trial / NCT00953849
Vitamin D Plus Celecoxib Therapy to Stimulate Intratumoral Immune Reactivity
RandomizedParallel-groupOpen-labelBasic science
Summary
The poor survival of Veterans with oral cancer underscores the significance of identifying new treatment approaches. The proposed studies will test a new 2 pronged immunotherapeutic approach for oral cancer patients which lessen the immune inhibitory environment while maturing cells that can stimulate T cell reactivity against oral cancer cells.
Timeline
- Start
- 2009-11
- Primary completion
- 2015-12
- Completion
- 2015-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Calcitriol | Small molecule | 4 ug | Other |
| Subject | Celecoxib | Other / unclassified | 400 mg | — |