drugset / Trial / NCT00955292

Dose-escalation Study of Quarfloxin in Patients With Advanced Solid Tumors or Lymphomas

NCT00955292 ↗

Phase 1 Terminated 12 enrolled Cylene Pharmaceuticals
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This phase 1 study of quarfloxin (CX-3543) is designed to test the safety, tolerability, and highest safe dose of this drug when administered intravenously weekly for three weeks of a four week cycle in patients with advanced solid tumors.

Timeline

Start
2007-07
Primary completion
2008-04
Completion
2008-12

Outcome

Outcome not reported

Stopped: “Modified dose schedule presented no advantage over previously studied schedule”

Drugs

EvaluationDrugModalityDoseRoute
Subject Quarfloxin Small molecule — Intravenous

Indications