Naturlose (D-Tagatose) Efficacy Evaluation Trial

Summary

The purpose of this trial was to evaluate the effectiveness and safety of Naturlose (Tagatose) for glycemic control in people with Type 2 diabetes who were not taking other medications for the condition and who were under diet control and exercise. The study lasted approximately one year. HbA1c was monitored every 2 months after entry into the study. Safety and tolerance for tagatose were assessed every 2 months throughout the study. A total of 14 visits were made to the study site.

Timeline

Start

2007-04

Primary completion

2010-10

Completion

2010-10

Outcome

Met primary endpoint

registry analysis (superiority or other test); Sugar Substitute Splenda vs Tagatose; p <0.05; Mean Difference (Net) 0.5; ANCOVA NCT00955747 ↗

Publications

• Lohner S, Kuellenberg de Gaudry D, Toews I, Ferenci T, Meerpohl JJ. Non-nutritive sweeteners for diabetes mellitus. Cochrane Database Syst Rev. 2020 May 25;5(5):CD012885. doi: 10.1002/14651858.CD012885.pub2.

Drugs

Indications