drugset / Trial / NCT00961844
Trial for Vaccine Therapy With Dendritic Cells in Patients With Metastatic Malignant Melanoma
Non-randomizedSingle-groupOpen-labelTreatment
Summary
In this trial the investigators want to combine chemotherapy with immunotherapy by giving the patients Temozolomide, before vaccination. The investigators have also included hTERT and survivin mRNA in the vaccine. Finally, the investigators want to introduce ex vivo T cell expansion after lymphodepletion for the patients who show an immune response.
Timeline
- Start
- 2009-08
- Primary completion
- 2012-06
- Completion
- 2012-06
Outcome
Outcome not reported
Stopped: “Logistical problems”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dendritic cells | Cell therapy | — | — |
| Subject | Temozolomide | Small molecule | — | — |