drugset / Trial / NCT00963495

Study Evaluating the Tolerance and Biological Activity of Oral Clioquinol in Patients With Relapsed or Refractory Hematological Malignancy

NCT00963495

Phase 1 Terminated 11 enrolled University Health Network, Toronto
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This is an open-label, single arm phase 1 study to evaluate the dose-limiting toxicity, maximum tolerated dose, and recommended phase II dose of Clioquinol in patients with relapsed or refractory hematologic malignancies. The study will also characterize Cliquinol's safety, tolerability and pharmacodynamic effect.

Timeline

Start
2009-08
Primary completion
2013-09
Completion
2013-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Clioquinol Small molecule 800 mg Oral