Study of Evaluation Indexes for Antibody Production in Sera After Immunization

Phase 4 Completed 70 enrolled Ewha Womans University

Parallel-groupOpen-label

Summary

The aim of this study is to evaluate analytical methods such as ELISA and OPKA that measure the activity of vaccine-induced pneumococcal antibodies. After validation of ELISA and OPKA, pneumococcal antibodies were measured by ELISA and OPKA in paired samples before and after immunization (pneumococcal PS vaccine) in children, adults and elderly.

Timeline

Start: 2005-04
Primary completion: 2005-05
Completion: 2005-06

Publications

Lee H, Nahm MH, Kim KH. The effect of age on the response to the pneumococcal polysaccharide vaccine. BMC Infect Dis. 2010 Mar 10;10:60. doi: 10.1186/1471-2334-10-60.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Pneumovax 23	Vaccine	0.5 ml	Intramuscular

Indications

No indication recorded.