drugset / Trial / NCT00964834
Ph1 Study of Valortim and Doxycycline in Humans
Phase 1
Terminated
24 enrolled
PharmAthene, Inc.
Department of Health and Human Services · collabMedarex · collabNational Institutes of Health (NIH) · collabQuintiles, Inc. · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
The purpose of this study is to evaluate the safety and tolerability of short-term dosing of IV doxycycline when administered concomitantly with IV Valortim in normal healthy human subjects.
Timeline
- Start
- 2009-07
- Primary completion
- 2009-10
- Completion
- 2009-12
Outcome
Outcome not reported
Stopped: “Sister trial has SAE investigation underway - sponsor elected to withdraw as study expected to be repeated later”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Doxycycline | Small molecule | 100 mg | Intravenous |
| Subject | MDX-1303 | Monoclonal antibody | 20 mg/kg | Intravenous |