drugset / Trial / NCT00967421

Development of a Valid Test Battery for Assessing Driving Ability When Influenced by Drugs.

NCT00967421 ↗

Non-randomizedCrossoverSingle-blindOther

Summary

The purpose of the validation study is to develop a valid test battery for assessing driving ability in a driving simulator when influenced by drugs. Ethanol has known, well-documented and well-characterized effects on driving behaviour and accident risk, and will be used to assess the simulator test scenarios' sensitivity to drug effects. Once the test scenarios have been refined and their ability to predict driving accident risk have been validated, we plan to use the simulator to assess driving ability under the influence of different drugs suspected to produce driving impairment.

Timeline

Start
2009-09
Primary completion
2009-11
Completion
2010-11

Outcome

Met primary endpoint

paper There was a positive dose-response relationship between higher ethanol concentrations and increases in SDLP in both the simulator and on the test track (p<0.001 for both). PMID 23357031 ↗

Drugs

EvaluationDrugModalityDoseRoute
Subject Ethanol Other / unclassified 2.4 g/kg Oral
Subject Ethanol Other / unclassified 3.6 g/kg Oral

Indications

No indication recorded.