drugset / Trial / NCT00969592
Expanded PK and PD of Insulin Glulisine Versus Insulin Aspart in Healthy Volunteers
RandomizedCrossoverDouble-blindBasic science
Summary
The purpose of this study was to compare the pharmacodynamics (course of the blood glucose-lowering effect and duration of effect) and pharmacokinetics (course of the concentration of study medication in the blood) of a single subcutaneous dose of 0.2 units/kg of insulin glulisine and insulin aspart in a direct head-to-head comparison during two euglycemic glucose clamps in healthy subjects.
Timeline
- Start
- 2007-11
- Primary completion
- 2007-12
- Completion
- 2008-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Insulin glulisine | Protein / enzyme biologic | 0.2 iu/kg | Subcutaneous |
| Comparator | insulin aspart | Protein / enzyme biologic | 0.2 iu/kg | Subcutaneous |