drugset / Trial / NCT00977769
Carbetocin Versus Oxytocin and Hemodynamic Effects
RandomizedParallel-groupQuadruple-blindTreatment
Summary
A randomized double-blind trial of oxytocin 5 u, carbetocin 100 µg and placebo with hemodynamic response as a primary outcome measure.
Timeline
- Start
- 2009-11
- Primary completion
- 2011-08
- Completion
- 2011-10
Publications
- Results Rosseland LA, Hauge TH, Grindheim G, Stubhaug A, Langesaeter E. Changes in blood pressure and cardiac output during cesarean delivery: the effects of oxytocin and carbetocin compared with placebo. Anesthesiology. 2013 Sep;119(3):541-51. doi: 10.1097/ALN.0b013e31829416dd.
- Michelsen TM, Tronstad C, Rosseland LA. Blood pressure and cardiac output during caesarean delivery under spinal anaesthesia: a prospective cohort study. BMJ Open. 2021 Jun 14;11(6):e046102. doi: 10.1136/bmjopen-2020-046102.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carbetocin | Peptide | 100 ug | — |
| Comparator | Oxytocin | Peptide | 5 iu | Intravenous |
Indications
No indication recorded.