drugset / Trial / NCT00981201
Celecoxib as a Chemopreventive Agent in Current and Former Smokers
RandomizedParallel-groupTriple-blindPrevention
Summary
The purpose of this study is: * To examine the effect of celecoxib treatment on Ki-67 expression, a marker of cell proliferation, in the bronchial epithelium of current and former smokers. * To examine the toxicity associated with celecoxib administration. * To measure the effect of celecoxib treatment on arachidonic acid metabolites in the bronchial epithelium of current and former smokers.
Timeline
- Start
- 2001-11
- Primary completion
- 2007-07
- Completion
- 2009-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Celecoxib | Other / unclassified | 200 mg | Oral |
| Subject | Celecoxib | Other / unclassified | 400 mg | Oral |
Indications
No indication recorded.