drugset / Trial / NCT00984932

Effect of Rosuvastatin on Systemic Sclerosis-related Pulmonary Hypertension

NCT00984932

Phase 3 Completed 40 enrolled University of Alexandria
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Although the aetiology of SSc-PAH remains elusive, vascular dysfunction seems to be the initial event and statins through their vasculoprotective effect might be of value in the treatment armamentarium of PAH related to SSc. The aim was to assess the efficacy of rosuvastatin in ameliorating vascular dysfunction and in the management of SSc-related PAH.

Timeline

Start
2008-09
Primary completion
2009-07
Completion
2009-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Rosuvastatin Small molecule 40 mg

Indications