drugset / Trial / NCT00986414

Evaluation of the Efficacy and Safety of AFQ056 in Reducing Moderate to Severe L-dopa Induced Dyskinesias in Patients With Parkinson's Disease

NCT00986414

Phase 2 Completed 260 enrolled Novartis
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This phase IIb study is designed to determine the safe and efficacious dose or dose range of AFQ056 for the treatment of patients with moderate to severe Parkinson's disease with L-Dopa induced dyskinesias.

Timeline

Start
2009-09
Primary completion
2010-12
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Mavoglurant Small molecule 10 mg
Subject Mavoglurant Small molecule 25 mg
Subject Mavoglurant Small molecule 50 mg
Subject Mavoglurant Small molecule 75 mg
Subject Mavoglurant Small molecule 100 mg